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We were particularly interested to determine the factors associated with complete remission. Methods: Eligible patients were followed up in the University College Hospital Lupus cohort from January until December for a period of at least 3 years. Complete remission was defined as a period of at least 3 years with clinical inactivity British Isles Lupus Assessment Group scores of C, D, or E only and laboratory remission no antibodies to double-stranded DNA and normal complement C3 levels , and being off-treatment with corticosteroids and immunosuppressants.
Antimalarial and nonsteroidal antiinflammatory drugs were allowed. MORE: Nine important facts about lupus you may not know Some lupus patients will suffer from mild symptoms constantly flares without any remission; others may have more severe symptoms but have periods of remission. MORE: Five strategies to help you manage lupus-related fatigue Lupus News Today is strictly a news and information website about the disease. Print This Page.
How useful was this post? Click on a star to rate it! As you found this post useful Follow us on social media! We are sorry that this post was not useful for you! Medications that had been used prior to remission included hydroxychloroquine, prednisone, azathioprine, mycophenolate mofetil Cellcept , cyclosporin, methotrexate, and rituximab Rituxan.
There were no differences in levels of remission reached according to age, sex, or disease duration. In a univariate analysis, factors that were associated with an inability to reach remission included the presence of vasculitis, serositis, hematologic abnormalities, glomerulonephritis, and positive anti-double stranded DNA antibodies.
Also in the univariate analysis, a history of glomerulonephritis was less common in patients who reached complete remission than in those who were in clinical remission either off or on steroids 6. On a multivariate analysis, these factors were associated with a failure to achieve persistent remission:.
An increase in SDI occurred in
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